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Prior oxygenation, but not chemoreflex responsiveness, determines breath‐hold duration during voluntary apnea
Contributor(s)
Christina D. Bruce (author); Emily R. Vanden Berg (author); Jamie R. Pfoh (author); Craig D. Steinback (author); Trevor A. Day (author); Library OA fund (funder)
Date issued
2021-01; 2021-01
Description
Central and peripheral respiratory chemoreceptors are stimulated during voluntary breath holding due to chemostimuli (i.e., hypoxia and hypercapnia) accumulating at the metabolic rate. We hypothesized that voluntary breath‐hold duration (BHD) would be (a) positively related to the initial pressure of inspired oxygen prior to breath holding, and (b) negatively correlated with respiratory chemoreflex responsiveness. In 16 healthy participants, voluntary breath holds were performed under three conditions: hyperoxia (following five normal tidal breaths of 100% O2), normoxia (breathing room air), and hypoxia (following ~30‐min of 13.5%–14% inspired O2). In addition, the hypoxic ventilatory...
Appears in collection(s)
Science and Technology