Mount Royal College has a longstanding commitment to information literacy as part of its mandate to promote student success and satisfaction. The library has provided course-integrated instruction in a variety of formats for over twenty years. Moving beyond course integration to program integration was a natural progression. Librarians and teaching faculty saw a need to plan sequenced sessions that would introduce students to incrementally complex information skills and resources throughout their academic careers. The librarians anticipated that integrating the instruction through the program would reduce unnecessary repetition, enhance student awareness of the myriad resources beyond the...
Oksana A. Yavorska (author); Lukas Syriste (author); Chantal M. du Plessis (author); Maryam Yaqoob (author); Kyle Loogman (author); Michael Cordara (author); John K. Chik (author); Library OA fund (funder)
Date issued
September 30, 2021; September 30, 2021
Description
Examining the effects of different cosolutes on in vitro enzyme kinetics yielded glimpses into their potential behavior when functioning in their natural, complex, in vivo milieu. Viewing cosolute in vitro influences on a model enzyme, calf intestinal alkaline phosphatase, as a combination of competitive and uncompetitive behaviors provided quantitative insights into their effects on catalysis. Observed decreases in the apparent specificity constant, Kasp, caused by the presence of polyethylene glycols or betaine in the reaction solution, indicated interference with enzyme–substrate complex formation. This competitive inhibition appeared to be driven by osmotic stress. Dextran 6 K and...