Jason S. Chan (author); Alexandra E. Chiew (author); Alexander N. Rimke (author); Garrick Chan (author); Zahrah H. Rampuri (author); Mackenzie D. Kozak (author); Normand G. Boulé (author); Craig D. Steinback (author); Margie H. Davenport (author); Trevor A. Day (author); Library OA Fund (funder)
Date issued
2021-08; 2021-08
Description
Normal blood [glucose] regulation is critical to support metabolism, particularly in contexts of metabolic stressors (e.g., exercise, high altitude hypoxia). Data regarding blood [glucose] regulation in hypoxia are inconclusive. We aimed to characterize blood [glucose] over 80 min following glucose ingestion during both normoxia and acute normobaric hypoxia. In a randomized cross-over design, on two separate days, 28 healthy participants (16 females; 21.8 ± 1.6 years; BMI 22.8 ± 2.5 kg/m2) were randomly exposed to either NX (room air; fraction of inspired [FI]O2 ~0.21) or HX (FIO2 ~0.148) in a normobaric hypoxia chamber. Measured FIO2 and peripheral oxygen saturation were both lower at...
